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BROAD EFFECTS OF REGULATORS. "These lines of evidence link VIP3 to stem thigmomorphogenesis. We also present evidence that other components of the Paf1 complex are required for thigmomorphic responses in both the stem and the root." https://lnkd.in/dv9swtZ View in LinkedIn

GENOTYPE ASSUMPTION. "One of the great challenges in molecular and evolutionary biology is to explain the link between giant evolutionary leaps, such as the colonization of land by plants or the emergence of vertebrates, and the underlying genetic and genomic changes. For a long time, biologists thought that such profound changes in phenotype would be accompanied—if not driven by—equally dramatic upheavals at the genetic level." https://lnkd.in/eNHFjJ8 View in LinkedIn

REGULATOR EVIDENCE. "We present four lines of evidence to support the conclusion that a lesion in VIP3 is responsible for the thigmomorphic defects seen in ths1 mutants." https://lnkd.in/dv9swtZ View in LinkedIn

REGULATION VS NOVELTY. "The great leap forward. Major evolutionary jumps might be caused by changes in gene regulation rather than the emergence of new genes." https://lnkd.in/eNHFjJ8 View in LinkedIn

OTHER REGULATORS. "We also show that THS1/VIP3 is required for both global and genic levels of H3K36 methylation and for upregulation of two canonical touch-inducible loci in response to touch stimulation." https://lnkd.in/dv9swtZ View in LinkedIn

NEW GENES. How do they arise? Are there gene life cycles in evolutionary terms? What permits some to persist? And, how do genes die and become extinct? How is all this regulated within the genome? View in LinkedIn

REFORMULATED GENES. "Many de novo genes have been discovered close to or overlapping older genes. This may reflect a reuse of pre-existing regulatory sequences." https://lnkd.in/dPqZs3m View in LinkedIn

JUNK DNA TO NEW GENES. "De novo genes are usually defined as protein-coding genes that have evolved from scratch from previously non-coding DNA. There are significant challenges surrounding the accurate detection of de novo genes." https://lnkd.in/dPqZs3m View in LinkedIn

EMERGENCE OF NEW GENES. "How new genes emerge and functionally diversify are very fundamental questions in biology, as new genes provide the raw material for evolutionary innovation that allows organisms to adapt, increase in complexity, and form new species." https://lnkd.in/e3rTkFh View in LinkedIn

SPECIATION DRIVER. "Evolution is the process by which all life on Earth has differentiated itself. It is what has separated whales from willows and butterflies from bacteria. Mutation drives this process by introducing occasional mistakes in gene sequences. These errors sometimes give an organism a selective advantage, and are thus passed down to later generations through natural selection." https://lnkd.in/dAgxYcj View in LinkedIn