linkedin post 2017-11-17 05:12:13

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GENE DOSAGE. "Although the notion that dioecy may be controlled by simple mutations affecting male or female functions may hold true for some simple plant systems, the situation is clearly more complicated in the case of those dioecious plants which have developed sex chromosomes of the X to autosome dosage type, where dosage sensing mechanisms involving genes analogous to the numerator and denominator genes found in drosophila have developed." https://lnkd.in/gb3zS32 View in LinkedIn
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linkedin post 2017-11-18 04:49:47

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NO COMMON THREADS. “Studying viral sequences means working at the edge of human knowledge. Even microbial genomics experts working on uncultivated microbes use the term “dark matter” when describing the viral sequences they find in metagenomes. While metagenomics expands our ability to detect viruses, a combination of small viral sequence databases and great diversity still means that many viral reads have no homology to known viruses.” https://lnkd.in/g35Hmrp View in LinkedIn
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linkedin post 2017-11-18 04:46:41

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BACKLOG. The International Committee on Taxonomy of Viruses (ICTV). “In the current (2013) ICTV taxonomy, 7 orders have been established, the Caudovirales, Herpesvirales, Ligamenvirales, Mononegavirales, Nidovirales, Picornavirales, and Tymovirales. The committee does not formally distinguish between subspecies, strains, and isolates. In total there are 7 orders, 103 families, 22 subfamilies, 455 genera, about 2,827 species and over 4,000 types yet unclassified.” https://lnkd.in/eF3wTsF View in LinkedIn
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linkedin post 2017-11-18 04:43:31

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VIRAL DARK MATTER. “Our understanding of viral diversity and virus–host interactions remains a major bottleneck in the development of predictive ecosystem models and unifying eco-evolutionary theories. This is because the lack of a universal marker gene for viruses hinders environmental survey capabilities, while the number of isolate viral genomes in databases remains limited: for comparison, more than 25,000 bacterial and archaeal host genomes are available in NCBI RefSeq (January 2015), whereas only 1,531 of their viruses were entirely sequenced and most (86%) of these derive from only 3 of 61 known host phyla.” https://lnkd.in/gQQCawV View in LinkedIn
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