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SMALL CHANGES, VAST EFFECTS. "Alternative splicing regulates the localization of proteins, their enzymatic properties and their interaction with ligands. In most cases, changes caused by individual splicing isoforms are small. However, cells typically coordinate numerous changes in ‘splicing programs’, which can have strong effects on cell proliferation, cell survival and properties of the nervous system." http://www.sciencedirect.com/science/article/pii/S0378111912009791 View in LinkedIn

REGULATORY KINGDOM. "Experimental analysis of these protein isoforms showed that alternative splicing regulates binding between proteins, between proteins and nucleic acids as well as between proteins and membranes." http://www.sciencedirect.com/science/article/pii/S0378111912009791 View in LinkedIn

ALTERNATIVE SPLICING IN PLANTS. "Epigenetic control of alternative splicing. Alternative splicing affects protein complexity and transcript levels and stability. Alternative splicing in the plant circadian clock. Alternative splicing diversity in ecotypes and polyploids." http://www.sciencedirect.com/science/article/pii/S1360138512001276 View in LinkedIn

PLANT SPLICING. "More than 60% of intron-containing genes undergo alternative splicing (AS) in plants. This number will increase when AS in different tissues, developmental stages, and environmental conditions are explored." http://www.sciencedirect.com/science/article/pii/S1360138512001276 View in LinkedIn

MOST GENES. "Almost every gene undergoes alternative splicing, which increases mRNA diversity." http://www.sciencedirect.com/science/article/pii/S0378111912009791 View in LinkedIn

FUNCTIONS NOT KNOWN. "Alternative splicing plays a key role in the expansion of proteomic and regulatory complexity, yet the functions of the vast majority of differentially spliced exons are not known." http://www.sciencedirect.com/science/article/pii/S1097276512004820 View in LinkedIn