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THE NUANCES. “A number of studies have established the effects of solar-geomagnetic activity on the human cardio-vascular system. These findings suggest that the heliophysical conditions before or after the admission affect the hazard ratio of lethal outcome; adjusting for clinical variables, these effects were stronger for women and older patients.” https://lnkd.in/dRix2gd View in LinkedIn

TIED TO THE COSMOS. “These findings add to the growing evidence that solar magnetic storm periodicities are mirrored by cyclic phase-locked rhythms of similar period length or lengths in human physiology and pathophysiology.” http://online.liebertpub.com/doi/abs/10.1089/ast.2010.0574 View in LinkedIn

PERIODICITY IN PATHOLOGY. “After determining that sunspot numbers and solar flux, which were not annually rhythmic, occurred with a prominent 10-year and a less-prominent 5.75-year periodicity during this 21-year study span, each biological data set was analyzed with the same curve-fitting procedures. All six annually rhythmic Pap smear-detected infectious, premalignant and malignant cervical epithelial pathologies showed strong 10-year and weaker 5.75-year cycles, as did all six self-measured, annually rhythmic, physiologic functions.” http://online.liebertpub.com/doi/abs/10.1089/ast.2010.0574 View in LinkedIn

BOTH EXTREMES. “Study linking environmental physical activity levels and the human medical data shows that human beings are predisposed to adverse health effects due to geomagnetic and cosmic ray activity variations and extremely high as well as extremely low values of GMA have health effects.” (GMA = geomagnetic activity). http://file.scirp.org/Html/6-8202044_31922.htm View in LinkedIn

CLOCK GENE REGULATION. “Recent evidence suggests that peripheral clock gene expression is subject to local metabolic (including aging) and mechanical stimuli, which also lead to epigenetic alterations underlying cellular dysfunction. In liver, pancreas, and adipose tissue, for example, the clocks can be influenced by the metabolic rate.” https://lnkd.in/dvGxeQP View in LinkedIn

CLOCK GENE LOCATION. “We now know that the central clock genes in the suprachiasmatic nuclei (SCN) are primarily entrained by light, and SCN outputs synchronize peripheral clock genes in cells of other tissues. The clock machinery is comprised of oscillatory positive and negative transcriptional-translational feedback loops involving the clock-related genes and their products.” https://lnkd.in/dvGxeQP View in LinkedIn

CLOCK GENES. "Mammalian circadian rhythms are driven by endogenous biological oscillators, the biological clock. Major molecular insight into the biological clock has been gained since the identification and cloning of the first clock genes.” https://lnkd.in/dvGxeQP View in LinkedIn

NO SUCCESSION PLAN. “To give another metric of the academic maturity of the field: ​only five people in the US have ​ever​ received PhDs in the physical sciences for dissertations whose primary focus was SETI​, only two of whom are astronomers today. Four were trained at Harvard by Paul Horowitz, eventually building a dedicated optical SETI observatory. The fifth is Andrew Siemion, trained in radio astronomy at Berkeley by Dan Werthimer and Geoff Bower—today Dr. Siemion serves as the director of the Breakthrough Listen SETI project and as the Oliver Chair for SETI Research at the SETI Institute.” https://lnkd.in/djnMhU6 View in LinkedIn

Coin shell fossils in Girona limestone. View in LinkedIn

CATCH-22. “One reason for this is that because the field has been largely funded philanthropically, much of the work has happened outside of academia and outside the aegis of the NSF, which strongly supports training as part of its scientific efforts. What SETI work has been done since 1960 has thus not been accompanied by a proportional amount of student training or formal curricular development, and has happened largely outside of academic publish-or-perish culture.” https://lnkd.in/djnMhU6 View in LinkedIn