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BILATERAL CROSSCHAT. "The host may also use chemical sensing to monitor microbial activity...a direct link between secreted bacterial products and chemosensory activation mechanisms for mucosal clearance." At the same time salivary and gingival antibodies play a key role in microbial colonization in the mouth. https://lnkd.in/egd9rZS View in LinkedIn

SYMMETRY BREAKING AND LACK OF CONSTRAINTS. "The spectrum of electromechanical phenomena on the molecular and nanoscale levels is much richer than in the macroscopic systems owing to symmetry breaking at surfaces and interfaces, the lack of constraints imposed by the lattice in low-dimensional and soft condensed-matter systems, and the absence of macroscopic averaging." https://lnkd.in/efupmXS View in LinkedIn

"SYMMETRY BREAKING in physics describes a phenomenon where (infinitesimally) small fluctuations acting on a system which is crossing a critical point decide the system's fate, by determining which branch of a bifurcation is taken...such transitions usually bring the system from a symmetric but disorderly state into one or more definite states. Symmetry breaking is supposed to play a major role in pattern formation." https://en.m.wikipedia.org/wiki/Symmetry_breaking View in LinkedIn

SECRET OF TEXTURE. "The secret of nature is symmetry, but much of the texture of the world is due to symmetry breaking." http://www.pnas.org/content/93/25/14256.full View in LinkedIn

MEANING OF SYMMETRY. "Einstein's great advance in 1905 was to put symmetry first, to regard symmetry as the primary feature of nature that constrains the allowable dynamic laws. With the development of quantum mechanics in the 1920s symmetry came to play an even more fundamental role." https://lnkd.in/b-9TDnm View in LinkedIn

CHACUN À SON GOÛT. "Taste receptor variants have been associated with differences in taste perception, alcohol consumption, and tobacco use." https://lnkd.in/ewWCUSe View in LinkedIn

AGING AND INFLAMMATION. "Prolonged exposure to high levels of circulating TNF compromises the integrity of the BBB. Sensitive techniques now detect the “asymptomatic” presence of bacteria in areas previously thought to be sterile...These “immune-tolerated” bacteria may slowly multiply elsewhere until they elicit a chronic inflammatory response." https://lnkd.in/e-V8G86 View in LinkedIn

ORAL BIOME AND AGING. "Immunosenescence results in increased bacterial load as cell-mediated and humoral immune responses wane. The innate immune system gradually takes over; contributing to the rise in circulating proinflammatory cytokines such as TNF. Maintaining the integrity of the blood-brain barrier (BBB) against a backdrop of increasing bacterial load is important." http://www.researchgate.net/profile/Deborah_Shoemark/publication/264794791_The_Microbiome_and_Disease_Reviewing_the_Links_between_the_Oral_Microbiome_Aging_and_Alzheimer's_Disease/links/53fd9d340cf22f21c2f816ab.pdf View in LinkedIn

ORAL MICROBIOME AND BLOOD-BRAIN BARRIER. "We propose for a subset of AD patients, aging favors the overgrowth of oral anaerobes established earlier in life provoking a pro-inflammatory innate response that weakens the BBB allowing bacteria to spread and quietly influence the pathogenesis of AD." http://www.researchgate.net/profile/Deborah_Shoemark/publication/264794791_The_Microbiome_and_Disease_Reviewing_the_Links_between_the_Oral_Microbiome_Aging_and_Alzheimer's_Disease/links/53fd9d340cf22f21c2f816ab.pdf View in LinkedIn

TASTE RECEPTOR AND METABOLISM. "TAS2R haplotype is associated with altered glucose and insulin homeostasis...a functionally compromised TAS2R receptor negatively impacts glucose homeostasis, providing an important link between alimentary chemosensation and metabolic disease." http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597743/ View in LinkedIn