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SUPERFAMILY. "Eukaryotes used glutamate or some other amino acid as a signalling molecule before they evolved nervous systems." https://lnkd.in/etGHsGm View in LinkedIn

SUPERFAMILY. "The ionotropic glutamate receptors comprise a related gene superfamily, which consists not only of NMDA, AMPA and kainate receptors but also of a more primitive plant variety of glutamate receptor." https://lnkd.in/etGHsGm View in LinkedIn

NMDA. "D-aspartate is a major regulator of adult neurogenesis and D-serine acts as a co-agonist of the N-methyl D-aspartate-type glutamine receptor in the brain, which are involved in learning, memory and behavior in mammals." https://lnkd.in/eXp7iyx View in LinkedIn

DIETARY D-AMINO ACIDS. "Food stores are now selling increasing quantities of foods (such as breakfast cereals, baked potatoes, liquid and powdered infant foods, meat substitutes and other supplements) which in some cases contain substantial quantities of D-amino acids, which in turn possess characteristics harmful with respect to digestion and health." https://lnkd.in/eNSAN8h View in LinkedIn

"D-AMINO ACIDS in peptides are well known as opioid peptides and neuropeptides. In protein, D-aspartate residues increase during aging." https://lnkd.in/e7QJSwN View in LinkedIn

"FREE D-ASPARTATE and D-serine are present and may have important functions in mammals." https://lnkd.in/e7QJSwN View in LinkedIn

NEW MARKERS. "D-Ser and D-Ala bind to the glycine site of NMDA receptors in the central nervous system. Both D-Ser and D-Ala are noted as novel candidate biomarkers of neuronal diseases, and novel therapies focusing on these two D-amino acids are also expected." https://lnkd.in/e7enTMS View in LinkedIn

FROG D-AMINO ACIDS. "Dermorphine was the first D-amino acid-containing peptide isolated from the skin of a frog; it is provided with an analgesic activity a thousand times greater than that of morphine." https://lnkd.in/eVWBM_B View in LinkedIn

ANIMAL D-AMINO ACIDS. "The first reports on D-amino acids in animal tissues were restricted to amphibians and invertebrates." https://lnkd.in/eVWBM_B View in LinkedIn

RECENT FINDING. "D-amino acids were recently found in various living higher organisms in the form of free amino acids, peptides, and proteins." https://lnkd.in/e7QJSwN View in LinkedIn