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SYDNEY BRENNER, while at the Cambridge MRC Unit in 1961 discussed the primary assumption that DNA contains the genetic information for protein synthesis, as do other downstream molecules like mRNA and others. https://lnkd.in/eCSzcsG View in LinkedIn

"THE CENTRAL DOGMA of molecular biology deals with the detailed residue-by-residue transfer of sequential information. It states that such information cannot be transferred from protein to either protein or nucleic acid. (Crick 1970). https://lnkd.in/eXBPqD5 View in LinkedIn

CARRIERS AND PROCESSORS. "In biology, organisms are often conceived of as informational systems, DNA as carriers of “genetic information”, and the brain is considered to be an extremely powerful information processor." https://lnkd.in/e-VqAeg View in LinkedIn

CENTRAL CURRENCY FOR FITNESS. "The quantification of the information content of genes and proteins and how this information may have evolved along the branches of the tree of life. Information is the central currency for organismal fitness, and appears to be that which increases when organisms adapt to their niche. Information about the niche is stored in genes, and used to make predictions about the future states of the environment." https://lnkd.in/ePx8EJu View in LinkedIn

INFORMATION ACQUISITION. "If inherited genetic material represents information, then how did the information-carrying molecules acquire it? Is the amount of information stored in genes increasing throughout evolution, and if so, why?" https://lnkd.in/ePx8EJu View in LinkedIn

PHYSICAL INFORMATION. "Information is often described as something that aids in decision making...One of the insights that has emerged from the theory of computation is that information must be physical—information cannot exist without a physical substrate that encodes it... In computers, information is encoded in zeros and ones, which themselves are represented by different voltages on semiconductors." https://lnkd.in/ePx8EJu View in LinkedIn

WHAT IS BIOLOGICAL INFORMATION? We may fairly assume that biological information has a structural basis. Is it the sequence of nucleotides, as in DNA, or the 3D structure, as in prions? Or perhaps it is more subtle, at a quantum mechanical level, at the level of electron spins, as researchers have been finding for selected systems. View in LinkedIn

THREE LEGS TO THE STOOL. "Life is a delicate interplay of energy, entropy, and information; essential functions of living beings correspond to the generation, consumption, processing, preservation, and duplication of information." https://lnkd.in/e6SKFbD View in LinkedIn

DEFECTIVE INTERFERING PARTICLES "(DIPs) are derived from and associated with their parent virus, and particles are classed as DIPs if they are rendered non-infectious due to at least one essential gene of the virus being lost or severely damaged as a result of the defection." https://lnkd.in/ejcrqcC View in LinkedIn

SPACE AND TIME. "In networks involving regulation, signaling, and metabolism, information is exchanged in space and time for decision making, thus timeliness of information delivery along with reliability and complexity constitute the basic objective." https://lnkd.in/e6SKFbD View in LinkedIn