linkedin post 2016-03-13 06:55:54

Uncategorized
VIRUS DEPENDENCY ON HOST ATP. "Several viral factors of VV utilize ATP and several steps in viral multiplication of VV require ATP. ATP is also required for DNA packaging and capsid maturation of herpes simplex virus, for capsid assembly and release of type D retrovirus, for capsid assembly of human immunodeficiency virus, and for budding of influenza virus." https://lnkd.in/ekemmeQ View in LinkedIn
Read More

linkedin post 2016-03-13 06:53:52

Uncategorized
VACCINA VIRUS INFECTION. "~90% of the host genes were down-regulated after VV infection, including genes involved in DNA replication, transcription, translation, apoptosis, and the proteasome-ubiquitin degradation pathway. Only a smaller fraction of host genes were up-regulated after VV infection, including WASP protein, and genes implicated in immune responses." https://lnkd.in/ekemmeQ View in LinkedIn
Read More

linkedin post 2016-03-13 06:46:50

Uncategorized
EXPROPRIATION. "In order to survive and replicate in the cell, viruses need to take control of the various cellular organelles involved in defense and immune processes. They also require energy to replicate and escape from the cell. Once inside the host cell, they modulate various cellular signal pathways and organelles, including mitochondria, and use them for their own survival and replication." https://lnkd.in/eFuy4KS View in LinkedIn
Read More

linkedin post 2016-03-15 05:11:45

Uncategorized
ENDOGENOUS VIRAL ELEMENTS (EVEs) "that are neutral or only slightly deleterious in their hosts may fortuitously drift or hitchhike to fixation, accumulating mutations at the host neutral rate. Alternatively, EVE insertions may confer an advantageous phenotype on the host and spread through the population by selection." https://lnkd.in/bBjWGE5 View in LinkedIn
Read More

linkedin post 2016-03-13 06:43:31

Uncategorized
LATENT VIRUSES. "Not every virus wants to go viral right away -- some want to wait for the perfect opportunity to attack. So the virus has to find a way to enter the cells of the human body without tripping the alarm. It's how viruses in the herpesvirus family, like human cytomegalovirus (HCMV), do their business." https://lnkd.in/eW2hh6T View in LinkedIn
Read More

linkedin post 2016-03-13 06:40:22

Uncategorized
PERSISTENT AND FREQUENT. "Between 50 and 80 percent of people in the U.S. have been infected by HCMV by the time they reach 40. Infections are rarely serious, but the virus does not leave the body. CMV is also the most common congenital infection in the U.S., and occurs when a mother contracts CMV during pregnancy and passes the virus to her unborn child." https://lnkd.in/eW2hh6T View in LinkedIn
Read More