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ARTIFICIAL BONE for dental and orthopedic surgeries has been a challenging major unmet need in medicine. New bone implants must conform perfectly to anatomic geography, not be rejected by the body, and have some of the remarkable strength and flexibility properties of natural bone. Strategies to achieve this have included bone glues, collagens, and bone grafts to recruit stem cells and growth factors. New seeding technologies using nano ceramics are also under investigation. As yet there is no perfect solution. View in LinkedIn

IPO markets in healthcare continue to be open, while seasoned observers keep an eye out for a weakening trend. Regardless, this is a real marker in the sand that the "nuclear winter" of the past five plus years has been broken. http://lnkd.in/kRSBSC View in LinkedIn

3D PRINTING applied to orthotic devices. So far we have seen a number of medical applications for this cunning technology, and this will not be the end. http://lnkd.in/PCSXbg View in LinkedIn

Ireland has a population of 4.5 M and yet this year alone they incorporated 6,500 new companies. Can this be a comeback to the heydays of Ireland, when it was attracting businesses due to lower tax and passport access? Impressive View in LinkedIn

NANO + PHARMA = OPPORTUNITY http://lnkd.in/qaURtg View in LinkedIn

Consolidation among mid-sized specialty Pharma companies continues to shrink this pool of companies. Now there are just a handful of players who have not been merged or bought, and the likelihood is that the trend will continue. This is particularly true for those companies like Activis whose strategy is growth by acquisition not by slow organic growth. This should be interesting reading in the coming two years. http://lnkd.in/M_kVHJ View in LinkedIn

HEART ATTACK predictive markers have been sought for decades, and in the typical clinical lab, muscle markers are only diagnostic after the MI has occurred. Fatal or severe acute event predictive tests are well suited to Point-of-Care diagnostic systems for at-risk patients (family history, prior history, metabolic profile). http://lnkd.in/MgYtYw View in LinkedIn

THE FLATWORLD EDUCATION MOVEMENT is in high gear as online education goes really global. Watch this space! http://lnkd.in/ZXk7Fq View in LinkedIn

NEW VISION for visually impaired using a smart micro-camera on glasses which reads text aloud to the user and learns from the user to recognize new things. This brilliant innovation will undoubtedly help millions of people, relatively inexpensively, who suffer from visual defects. http://lnkd.in/RtR4YY View in LinkedIn

FDA 483 Warning Letters are becoming quite frequent for pharmaceutical manufacturers, and the consequences can be dire in the worst case. Unfortunately, the "right way" to respond is complicated. For sure, there are legions of experts and consulting firms, who can be very valuable. But at the end of the day, after all the consultants and lawyers have had a go at the response, it is critical to ask if the company and the FDA are on the same planet in terms of communicating. Frequently not. http://lnkd.in/D4Z2TF View in LinkedIn