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FETAL TRANSFER. "The presence of plant miRNAs in fetal umbilical cord blood and amniotic fluid suggests that exogenous miRNAs could transfer through the placenta to the fetal side. Plant miRNAs were also found in the mouse fetuses by quantitative RT-PCR." https://lnkd.in/eA6-J-S View in LinkedIn

miRNA PLACENTAL TRANSFER. "Small non-coding RNAs transfer through mammalian placenta and directly regulate fetal gene expression...we were surprised to find exogenous plant miRNAs in human umbilical cord blood and amniotic fluid. In conclusion, the present study provides the first evidence that small non-coding RNA can be transplacentally transmitted from the mother to the fetus." https://lnkd.in/eA6-J-S View in LinkedIn

MILK YES, RICE NO? "While the evidence in support of bioavailability of milk miRNAs is unambiguous, a recent report that mammals can also absorb plant miRNAs (e.g. miR-168a) from rice was met with widespread skepticism." https://lnkd.in/ej7XF-E View in LinkedIn

"MARINE MAMMALS from different mammalian orders share several phenotypic traits adapted to the aquatic environment and therefore represent a classic example of convergent evolution. Our comparative genomic analyses found that convergent amino acid substitutions were widespread throughout the genome and that a subset of these substitutions were in genes evolving under positive selection and putatively associated with a marine phenotype." https://lnkd.in/eBMUXjN View in LinkedIn

"EXOSOMES are small extracellular vesicles released by cells and play important roles in intercellular communication and pathogen transfer. Exosomes have been implicated in several neurodegenerative diseases, including prion disease and Alzheimer’s disease." https://lnkd.in/ea-rNpb View in LinkedIn

SHIFT IN MODALITY. "Many of these changes are in genes that may be associated with the shift in primary sensory modality (between vision and echolocation), either directly or through the associated complex changes in ecology and natural history." https://lnkd.in/epGtvrz View in LinkedIn

DIETARY MICRO-RNA. "It has been recently discovered that human can absorb certain exosomal microRNAs from cow’s milk." https://lnkd.in/ej7XF-E View in LinkedIn

VISION AND ECHOLOCATION. "Our genome-wide analysis shows that natural selection has acted on three echolocating lineages (cetaceans and two separate bat lineages) to produce a complex pattern of changes in protein sequence, including both divergent and, more surprisingly, extensive convergent changes." https://lnkd.in/epGtvrz View in LinkedIn

COW MILK. "Recently Zempleni and co-workers have demonstrated that humans seem to absorb cow milk derived microRNAs in significant concentrations and that these microRNAs seem to affect gene expression in human white blood cells, cultured kidney cells, and mouse liver." https://lnkd.in/erkHGt5 View in LinkedIn

ECHOLOCATION. "Here we analyse genomic sequence data in mammals that have independently evolved echolocation and show that convergence is not a rare process restricted to several loci but is instead widespread, continuously distributed and commonly driven by natural selection acting on a small number of sites per locus." https://lnkd.in/epGtvrz View in LinkedIn