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VIRAL GENOME EDITING VITAL TO ALL LIFE. "Contemporary sequence analyses and intercomparisons underline the crucial evolutionary functions of viruses and their genome-editing competences for all life forms." https://lnkd.in/e-pJFM6 View in LinkedIn

RNA AGENTS AND VIRUSES. "It seems plausible now that if we look at the abundance of regulatory RNAs and persistent viruses in host genomes, we will find more and more evidence that the key players that edit the genetic codes of host genomes are consortia of RNA agents and viruses that drive evolutionary novelty and regulation of cellular processes in all steps of development." https://lnkd.in/eUYvi8e View in LinkedIn

CONTRARY TO DARWIN. "Evolutionary history emerges entirely differently than previously thought. This history is not an aggregation of chance mutations of the genetic text and its associated selection. Rather, it is a permanent and competent processing of genetic sequences to acquire previously unknown abilities and to ward off competing parasites via genomic innovation." https://lnkd.in/e-pJFM6 View in LinkedIn

NO GRADUAL MUTATION. "I would certainly go along with the view that gradual mutation followed by selection has not, as a matter of fact, been demonstrated to be necessarily a cause of speciation." (Professor Denis Nobel). https://lnkd.in/eSeZ5Qq View in LinkedIn

RULES OF SYNTAX. "Combinatorial and rearranging processes in evolutionary and developmental processes occur non-randomly. They need successful and coherent adherence to the rules of molecular syntax." https://lnkd.in/e-pJFM6 View in LinkedIn

GENOME EDITING IS IMPORTANT. "There is growing evidence that natural genome-editing competences of viruses are essential for the evolution of the eukaryotic nucleus, the adaptive immune system and the placental mammals." https://lnkd.in/e-pJFM6 View in LinkedIn

CODES NEED ACTIVE AGENTS. "The variety of RNA agents that share the competence to act on nucleic acid sequences by several techniques (de novo generation, ligation/degradation, insertion/deletion, silencing, amplification, epigenetic markings, etc.) is coherent with the general assumption that no natural code codes itself but needs some competent agents that act on this code." https://lnkd.in/eg6uePF View in LinkedIn

KEY FIRST DISTINCTION. "Natural genome editors differentiate between self and non-self. How did prebiotic chemistry start life?" https://lnkd.in/eg6uePF View in LinkedIn

LYNN MARGULIS. "Called "Science's Unruly Earth Mother", a "vindicated heretic", or a scientific "rebel", Margulis was a strong critic of neo-Darwinism. Her position sparked lifelong debate with leading neo-Darwinian biologists, including Richard Dawkins, George C. Williams, and John Maynard Smith." She was married to astronomer Carl Sagan. https://lnkd.in/et3gdfj View in LinkedIn

UNINTENDED CONSEQUENCES. "Another explanation is that high nucleotide substitution rates are linked to reactive oxygen species (ROS) generated from the increased respiratory rates needed for the oxidative phosphorylation of ADP to ATP upon movement of trapping devices in carnivorous plants." https://lnkd.in/e4xhW7h View in LinkedIn