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REPETITIVE INTRONS OF JUNK DNA. "Nearly all genetic and genome editing processes involve RNAs, which in most cases function as a network. Most of the functions are performed, conducted, and regulated by noncoding RNAs, which are encoded in intronic DNA in most cases with repetitive syntax." (Junk used with irony). https://lnkd.in/euyhznh View in LinkedIn

DNA IS DYNAMIC. "Some decades ago, it became obvious that DNA is not an unchangeable information carrier, but is subject to dynamic interactional change that has essential relevance for evolutionary novelty. It has been found, that in some events, a duplication of genes happened." http://onlinelibrary.wiley.com/doi/10.1111/nyas.12570/abstract View in LinkedIn

JUNK BEGETS NOVELTY. "There are some indications that noncoding DNA plays a role in the de novo generation of genes." Smile at the reversals of history. https://lnkd.in/euyhznh View in LinkedIn

ADVANTAGEOUS ERRORS. "In an abundance of replication errors, in very few cases it may occur that one or a few are beneficial to prior master types. They have selective advantages, and the accumulation of such rare beneficial mutations is the driving force for variation, the core force that is subject to biological selection." http://onlinelibrary.wiley.com/doi/10.1111/nyas.12570/abstract View in LinkedIn

MULTIPLE MEANINGS. "During translation from digital DNA storage into the analog code of protein language it is interesting that DNA information contains multiple RNA- and protein meanings, that is, from the same genetic data set it is possible to transcribe multiple RNA species or translate a variety of proteins according to the higher order regulations inherent in epigenetic control and/or transcriptional, pre- or posttranscriptional modification targets." https://lnkd.in/euyhznh View in LinkedIn

REPLICATION ERRORS. "If information is really only physics and chemistry, then replication can only form identical copies. If changes occur that vary the master copy, the correct designation is error. Therefore, mutation as error replication is the appropriate term, because it is a statistical event, randomly derived." https://lnkd.in/bpZMBAH View in LinkedIn

IMMUNITY TO RETROVIRAL INFECTIONS. "As intron-rich linear chromosomes are the preferred habitat for persistent retroviral infections, and because of their important role in host-genetic content (re) arrangements, the invention of bacterial circular genomes must have had an effective immune function against retroviral infections. The result was the evolution of organisms that successfully escaped the high selective pressures of the early RNA world." https://lnkd.in/ekWBG2q View in LinkedIn

"HYPOTHESIS: micromessengers are agents of conflict between different interacting parties. The potential for miRNAs to function as micromessengers to effect cell-to-cell communication at a distance represents considerable potential for the expression of conflicts of interest." https://lnkd.in/eRcyMDJ View in LinkedIn

HIGHER LEVEL CONTROL. "But this text processing on protein-coding DNA is overruled by the genome processing abilities of repetitive DNA of introns coding not for proteins but a lot of RNAs among them active micro-RNAs. Typically, any mistakes in protein-coding and non-protein coding text processing have grave if not lethal consequences for the organism." https://lnkd.in/eDswHmC View in LinkedIn

LOW ERROR RATE WITH DNA. "No technical production system, regardless how perfect, even approaches the low error rate achieved in the DNA reproduction process in living organisms." https://lnkd.in/eDswHmC View in LinkedIn