Category: Uncategorized

QUASISPECIES CHALLENGED. "Our mainstream picture of RNA virus evolution is determined by the quasispecies concept of Manfred Eigen. It was a very helpful theoretical model within the framework of physical chemistry to paint a picture of viruses with an evolution rate a multitude faster than evolution of cellular organisms." https://lnkd.in/e6fRF6A View in LinkedIn

CONSORTIAL QUASI-SPECIES. "We must look at organisms as phenomena in which complex and dynamic “protein bodies” are regulated by RNA agents that build sequences that have new protein meanings and can act as consortial ribozymatic agents to create networks. The highly stable DNA cellular world is then an omnipresent, comfortable, chemically stable but enzymatically vacant habitat." https://lnkd.in/eUYvi8e View in LinkedIn

PHYSICAL VS BIOLOGICAL SELECTION. "Recent investigations surprisingly indicate that single RNA “stem-loops” operate solely by chemical laws that act without selective forces, and in contrast, self-ligated consortia of RNA stem-loops operates by biological selection." https://lnkd.in/e6fRF6A View in LinkedIn

SYNCHRONIZED SCALING. "The accumulation of junk DNA would indeed scale with accumulating RNA society complexity." https://lnkd.in/eUYvi8e View in LinkedIn

RNA STEM-LOOPS. "If we look at the “body” of these (RNA) social networks, we can see a secondary structure that is shared by all these RNA nucleic acid sequences: it is the stem-loop structure or, in the case of more complex agents such as tRNA or ribosomal subunits, the ligated consortia of such stem loops." https://lnkd.in/eUYvi8e View in LinkedIn

PROTEIN CODING INNOVATION. "RNA agents provide an unlimited potential for new productivity since there is no fundamental limit to be further parasitized by additional agents." https://lnkd.in/eUYvi8e View in LinkedIn

RNA AS SOCIAL NETWORK. "In this world of life processes actively dominated by RNA, DNA is increasingly cast in the role of the “house” of genetic information storage, whereas the interacting RNAs seem to be the “social network” within this house." https://lnkd.in/eUYvi8e View in LinkedIn

RNA AGENTS AND PROTEIN CODING. "It now seems plausible that the basic coding of proteins and their variable regulations (conserved in DNA) are the collective results of an abundance of complementary RNA agents." https://lnkd.in/eUYvi8e View in LinkedIn

NATURAL SELECTION IN RNA CONSORTIA. "Whereas the single stem-loop emergence seems to not be subjected to selection processes, the consortia that are built with these tools are subjected to selection processes." https://lnkd.in/eUYvi8e View in LinkedIn

STEM LOOPS. "They are not only remnants of the ancient RNA world but ongoing infection-derived modular tools for new cellular needs, that is, “domesticated” consortia of interacting RNA agents such as viruses, mobile genetic elements, and noncoding RNAs." https://lnkd.in/eUYvi8e View in LinkedIn