linkedin post 2016-10-04 06:08:34

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GENE DUPLICATION. "He proposed the now familiar concept that these polyploid plants were fertile because genome doubling restored chromosome pairing in otherwise sterile hybrids. The restoration of fertility to sterile hybrids by doubling their genomes was a potent and elegant demonstration of how postzygotic reproductive isolation could be solved." https://lnkd.in/e5Q_ate View in LinkedIn
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linkedin post 2016-10-04 05:57:19

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PARSING OLD GENES. "One of the primary goals of our work on gene duplication is to explain the shortcomings of the classical model, which postulates that the usual fate of a duplicated gene is either conversion to a nonfunctional pseudogene or acquisition of a new function. We believe that duplicate genes are frequently preserved through a partitioning of functions of ancestral genes (subfunctionalization), rather than by the evolution of new functions." https://lnkd.in/e8G48jD View in LinkedIn
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linkedin post 2016-10-03 05:17:57

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COMPLEXITY AND POPULATION SIZE. "Using population-genetic principles as a guide to understanding the evolution of duplicate genes, introns, mobile-genetic elements, and regulatory-region complexity, our work is advancing the hypothesis that much of eukaryotic genome complexity initially evolved as a passive indirect response to reduced population size (relative to the situation in prokaryotes)." https://lnkd.in/e8G48jD View in LinkedIn
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linkedin post 2016-10-08 05:16:20

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FRAGMENT FROM NATURE continues from last weekend exploring Darwin's "abominable mystery", the rise of flowering plants (angiosperms). There was no way Darwin could have known the full story: genes had not been discovered then. Their extraordinary diversity of their sexual organs (flowers), seed design, and the genetics driving them is fascinating. I touch on a bigger topic, whole genome duplication, that will be taken up in more detail in coming weeks. View in LinkedIn
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