FLIPPASES. “Phospholipid flip-flop is required for bilayer assembly and the maintenance of biogenic (self-synthesizing) membranes such as the eukaryotic endoplasmic reticulum and the bacterial cytoplasmic membrane. Due to the membrane topology of phospholipid biosynthesis, newly synthesized phospholipids are initially located in the cytoplasmic leaflet of biogenic membranes and must be translocated to the exoplasmic leaflet to give uniform bilayer growth.”
http://www.ncbi.nlm.nih.gov/pubmed/15809683
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022