linkedin post 2017-06-26 04:05:54

EPIGENETIC LINKS. “We showed that the methylation level in three cytosine contexts of MULE internal sequences increases and that the CHH context of MULE TIRs decreases over evolutionary time. This result implies that genic-MULEs which acquired potentially functional coding sequences and were maintained in the multiple Oryza species over millions of years might acquire epigenetic marks in their internal and TIR sequences that are needed to maintain their stability in the genome.” (MULEs = Mutator-like transposable elements; TIR = terminated inverted repeats).

http://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-0954-8

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