NON-MENDELIAN INHERITANCE examples include over 50 diseases, caused by: incomplete penetrance, allele interaction, epigenetic triggers, unusual segregation patterns, variable expressivity, twin effects, segregation distortion, triplet repeat expansion, telomere shortening, cryptic telomeres alleles, and maternal inheritance and heteroplasmy. Discussed in detail in this excellent review.
http://hmg.oxfordjournals.org/content/13/suppl_2/R225.full
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022