SPECKLES AND EPIGENETICS. “During mitosis, germ-cell granules shrink and disappear from the part of the cell that will become the soma, and fuse or enlarge in the part of the cell that will remain germline. The differentiation of somatic and germline daughter cells is determined in part by the absence or presence of germ-cell granules. These are also acquired to specify the germline in the next generation, which represents clear example of epigenetic inheritance.”