linkedin post 2017-08-27 06:58:14

OTHER SPAWN. “These ancient cellular genes, encoding cellular proteins with the HK97-like fold, might have independently given rise to the viral proteins with different topologies and insertional domains. Adaptation to more complex environments of higher level organisms such as animal cells could have naturally led to acquisition of additional structures by way of insertions at locations of the loops of the HK97-like fold, as revealed in eukaryotic viruses such as herpesviruses. Such insertional domains could also give rise to auxiliary proteins by way of gene splicing such as the proposed case between BPP-1 and P22-like phages.”

http://www.aimspress.com/article/10.3934/biophy.2015.2.200/fulltext.html

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