GENE PARADIGM SHIFTS. “Biology is no stranger to paradigm shifts. Before the advent of molecular biology, classical genetics was based on the notions that genes are the fundamental units of mutation, of recombination, and of heredity, and that they are arranged on the chromosomes like beads on a string. New insights, generated by molecular analysis, forced a recognition that there were, in fact, no fundamental units, no beads, and no string.”
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