APPLICATIONS IN CANCER. “A particularly compelling set of use cases for the application of systems biology to understand the genomics of disease can be found in cancer. Efforts to characterize the most prevalent mutations of various cancers by The Cancer Genome Atlas (TCGA) Research Network have revealed recurrent mutations in specific pathways.”
https://bmcsystbiol.biomedcentral.com/articles/10.1186/1752-0509-8-S2-S1