STRUCTURED PROXIMITY. “The spatiotemporal clustering of functionally related macromolecules increases the probability and rate of productive encounters. The enhanced specificity afforded by the cooperative interactions of multicomponent protein machines resolved questions of how weak, moderately specific interactions (e.g. transcription factor-DNA binding) became functional in vivo.”
http://onlinelibrary.wiley.com/doi/10.1111/febs.13744/full
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022