MASSIVE CORRELATIONS. “Among 481 compounds, we identified 329 compounds that have at least one significant correlation with clock genes, with 3,577 significant correlation pairs (Figure S7D). We found 163 compounds that showed significant correlation with at least 10 clock genes (Figure S7E), and 76 drugs are shared between the GDSC and CTRP databases. Among them, 53 drugs in both CTRP and GDSC have at least one pair that significantly correlates with clock genes. These results show the consistency of circadian effects on drug response.”
https://lnkd.in/dT2NKaY
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022