Year: 2022

THE MICROBIOME. “The gut microbiota has a central role in both metaflammation and inflammaging owing to its ability to release inflammatory products, contribute to circadian rhythms and crosstalk with other organs and systems.” https://www.nature.com/articles/s41574-018-0059-4 View in LinkedIn

FASTER AGEING. “We argue that chronic diseases are not only the result of ageing and inflammaging; these diseases also accelerate the ageing process and can be considered a manifestation of accelerated ageing.” https://www.nature.com/articles/s41574-018-0059-4 View in LinkedIn

BIOMARKERS OF AGEING. “Finally, we propose the use of new biomarkers (DNA methylation, glycomics, metabolomics and lipidomics) that are capable of assessing biological versus chronological age in metabolic diseases.” https://www.nature.com/articles/s41574-018-0059-4 View in LinkedIn

CONSERVED MECHANISM. “According to geroscience, inflammation is one of the seven evolutionarily conserved mechanistic pillars of ageing that are shared by age-related diseases, including metabolic diseases.” https://www.nature.com/articles/s41574-018-0059-4 View in LinkedIn

WORN OUT. “Inflammaging is the long-term result of the chronic physiological stimulation of the innate immune system, which can become damaging during ageing — a period of life largely unpredicted by evolution.” https://www.nature.com/articles/s41574-018-0059-4 View in LinkedIn

THE ISSUE OF SELF. “Inflammaging is the by-product of the degeneracy of a few receptors that can sense a variety of non-self, self and quasi-self damage signals (or ‘garbage’) and activate the innate immune system.” https://www.nature.com/articles/s41574-018-0059-4 View in LinkedIn

QUANTUM ENTANGLEMENT. “A wide range of animal species are capable of sensing (and, in some cases, extracting directional information from) the geomagnetic field. A strong candidate hypothesis for explaining these phenomena is the radical pair (RP) mechanism (RPM).” (Via Cryptochromes, which occur also in human cells). https://lnkd.in/dThgXrwZ View in LinkedIn

The lower levels of the huge walls that surround Girona were Roman and clearly quite different in construction technique and material. View in LinkedIn

NUTRIENT EXCESS. “Inflammaging and metaflammation largely share the same molecular mechanisms, in which metaflammation can be conceptualized as a specific situation of chronic inflammation caused by nutrient excess.” https://www.nature.com/articles/s41574-018-0059-4 View in LinkedIn

INTERACTING SYSTEMS. “The gut microbiota has a central role in metaflammation and inflammaging, as it can release inflammatory products and contribute to the circadian rhythms and crosstalk with other organs and systems.” https://www.nature.com/articles/s41574-018-0059-4 View in LinkedIn