linkedin post 2018-06-27 04:17:38

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SHAPE SPECIFYING FUNCTION. "Given that the molecular function of ncRNA may at least be partially conveyed through secondary or tertiary structures, mining evolutionary data for evidence of such features promises to increase the resolution of functional genomic annotations." (ncRNA = non coding RNA). http://nar.oxfordjournals.org/content/early/2013/07/11/nar.gkt596.full View in LinkedIn
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linkedin post 2018-06-26 03:34:52

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SEA CHANGE. "The majority of the human genome is dynamically transcribed into RNA, most of which does not code for proteins. The once common presumption that most non–protein-coding sequences are nonfunctional for the organism is being adjusted to the increasing evidence that noncoding RNAs (ncRNAs) represent a previously unappreciated layer of gene expression essential for the epigenetic regulation of differentiation and development." https://lnkd.in/guFKNHU View in LinkedIn
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