linkedin post 2016-03-16 04:51:07

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RARE VIRAL GROUP. "In eukaryotes, retroviruses, which can integrate into host genome as an obligate step in their replication strategy, comprise approximately 8% of the human genome. Unlike retroviruses, few members of other virus families are known to transfer genes to host genomes." http://www.biomedcentral.com/1471-2148/11/276/ View in LinkedIn
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linkedin post 2016-03-16 04:45:52

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A RETROVIRUS is "a virus that is composed not of DNA but of RNA. Retroviruses have an enzyme, called reverse transcriptase, that gives them the unique property of transcribing their RNA into DNA after entering a cell. The retroviral DNA can then integrate into the chromosomal DNA of the host cell, to be expressed there. HIV is a retrovirus." https://lnkd.in/eGM2VGa View in LinkedIn
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linkedin post 2016-03-17 04:57:48

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SHOT THROUGH. "Post-insertional recombinations, deletions, and mutations have rendered all known human endogenous retroviruses (HERVs) non-infectious. However some, particularly the most recently acquired proviruses of the HERV-K(HML-2) family, can expresses viral proteins and produce viral particles." http://journal.frontiersin.org/article/10.3389/fonc.2013.00246/full View in LinkedIn
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linkedin post 2016-03-15 05:14:49

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OBLIGATE STEP. "In animal genomes, the majority of EVEs are derived from reverse transcribing RNA (rtRNA) viruses (i.e. retroviruses). Retroviruses are the only animal viruses that integrate into the genome of the host cell as an obligate step in their replication strategy, and are thus predisposed to enter the host germ line." https://lnkd.in/bBjWGE5 View in LinkedIn
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linkedin post 2016-03-17 04:54:09

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FORENSIC TRACKS. "The discovery that a broad range of viruses are represented by EVEs in animal genomes indicates that viral ‘molecular fossils’ can provide the basis for robust, time-scaled, macroevolutionary studies across a range of animal and virus groups." https://lnkd.in/bBjWGE5 View in LinkedIn
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