Month: September 2022

RECREATING THE NEANDERTHAL. "Church speculated that it could be technically possible to make a Neanderthal by reconstructing the DNA of a Neanderthal and modifying living human cells accordingly."" " http://lnkd.in/d4Ys85G View in LinkedIn

CHURCH'S BOOK "Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves" says that it is now "possible to resurrect practically any extinct animal whose genome is known or can be reconstructed from fossil remains" as has been done for the wooly mammoth and Neanderthal man. View in LinkedIn

REANIMATION OF EXTINCT SPECIES. "The goal of reanimation research is not to make perfect living copies of extinct organisms, nor is it meant to be a one-off stunt in a laboratory or zoo. Reanimation is about leveraging the best of ancient and synthetic DNA. The goal is to adapt existing ecosystems to radical modern environmental changes, such as global warming, and possibly reverse those changes." (George Church)." " http://lnkd.in/dhjkN3m View in LinkedIn

DE-EXTINCTION "is not a novel idea. Medical researchers have resurrected the full genomes of the human endogenous retrovirus HERV-K and the 1918 influenza virus. Insight into these reanimated species could save millions of lives. Several other extinct genes, including for mammoth hemoglobin, have been reconstructed and tested for novel properties." (George Church). " " http://lnkd.in/dhjkN3m View in LinkedIn

JURASSIC PARK. "A team of Russian and South Korean scientists are, as of April 2013, attempting to clone a Woolly mammoth using an Elephant as a surrogate mother. Large amounts of well-preserved mammoth tissue have been found in Siberia, but, as of April 2013, the cloning process is still in the planning stages. Once the process is completed, there are plans to introduce the mammoths to Pleistocene Park, a wildlife reserve in Siberia."" " http://lnkd.in/d-xMhvm View in LinkedIn

COMPLETE REANIMATION OF EXTINCT VIRUSES. Endogenous retroviruses are very common in mammalian DNA, constituting about 8% of human DNA. These are mostly derived from extinct ancient viruses. Many research groups have reanimated these extinct retroviruses and generated infectious functional strains by inserting a part into a modern mouse retrovirus. In the case cited herein, the retrovirus was 4 million years old. " " http://lnkd.in/d7uANWP View in LinkedIn

RESURRECTION OF ANCIENT EXTINCT HUMAN RETROVIRUSES. "The genomes of most organisms are infested with repeat sequences derived from genomic parasites. In humans, repeat elements constitute ∼45% of the total genome. About 8% of these are contributed by the class of elements that replicate via an RNA intermediate including HERVS." These Human Endogenous Retroviruses (HERVs) have been successfully resurrected from extinction in the lab. " " http://lnkd.in/d-MgDBw View in LinkedIn

100 MILLION YEAR INSERTS IN HUMAN GENES by extinct retroviruses have been described. These are equally accessible to resurrection by demonstrated laboratory methods. " " http://lnkd.in/d2-NRF4 View in LinkedIn

RESURRECTION OF 1918 FLU, a lethal pandemic which killed the equivalent of the current UK population, and three times the number killed in WWI. "Scientists in the US say they have recreated the influenza virus that killed at least 50 million people in 1918, and they have infected mice with it." They reconstructed it from DNA in hospital samples and from a victim in Alaskan permafrost. Critical insights to bird flu were obtained. " " http://www.newscientist.com/article/dn8103-us-scientists-resurrect-deadly-1918-flu.html View in LinkedIn

CHURCH'S FOCUS TODAY. "When I asked Church what he was most excited about right now, he answered without hesitation: “I’m thinking a lot about using regeneration as the key to treatments and keeping people healthy.”" " http://lnkd.in/dWBcA_p View in LinkedIn