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RESOURCE. “Researchers can follow these genetic logic gates to explore how the input and output of genes, proteins and promoters are organized.” https://www.nature.com/articles/srep08090 View in LinkedIn

CURATED. “SynBioLGDB therefore provides a global view of genetic logic gates in synthetic biology.” https://www.nature.com/articles/srep08090 View in LinkedIn

DATABASE STATUS. “The current version of SynBioLGDB documents more than 180 logic gates across three species (Human, Escherichia coli and Bacillus clausii).” https://www.nature.com/articles/srep08090 View in LinkedIn

BIOBRICKS. “This database is aimed at gathering a comprehensive collection of experimentally validated logic gates by manually curating the literature (Figure 1).” https://www.nature.com/articles/srep08090 View in LinkedIn

DATABASE. “Because genetic logic gates are the basic building biobricks of electronic circuits we developed a synthetic biology database of experimentally validated logic gates (SynBioLGDB) to facilitate related research.” https://www.nature.com/articles/srep08090 View in LinkedIn

GENETIC LOGIC SYSTEMS. “Genetic logic gates are therefore at the core of the mechanism of synthetic biology, incorporating electronic engineering in cell biology, where biomolecular logic gates are necessary for generating genetic logic systems.” https://www.nature.com/articles/srep08090 View in LinkedIn

PROGRAMMABLE CELLS. “Thus, by designing customized genetic logic circuits to link various cellular sensors and actuators, we can program living cells to generate precise desired behaviours in response to specific extra or intra-cellular signalling inputs.” https://www.nature.com/articles/ncomms1516 View in LinkedIn

FROM ELECTRONS TO GENES. “Genetic logic gate devices communicate with each other through changes in gene expression and activity. For example, when a sensor is stimulated, this may lead to the activation of a promoter, which then acts as the input to a circuit.” https://www.nature.com/articles/srep08090 View in LinkedIn

CASCADE AND INTEGRATE. “As Boolean logic gates are widely used in electronic circuits to build digital devices, logic operations are encoded in gene regulatory networks that cells use to cascade and integrate multiple environmental and cellular signals and to respond accordingly.” https://www.nature.com/articles/ncomms1516 View in LinkedIn

TOOLBOX. “This could make it possible to decipher complex living systems and produce reliable behaviour in organisms through diverse genetic circuit modules.” https://www.nature.com/articles/srep08090 View in LinkedIn