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MECHANISM OF NOW. “ Whatever fraction of the wave function which has not yet been relevant to determining present reality continues in a superposition of states, thereby maintaining the framework of possibility from which the future crystallizes in the next instant.” https://lnkd.in/gDaxUYAS View in LinkedIn

DISRUPTION DURATION. “Similarly, reports suggest that the risk of prostate cancer is increased in night-shift workers, and this risk is augmented with a longer duration of shift work, particularly for high-grade cancers.” https://www.nature.com/articles/s41591-018-0271-8?fbclid=IwAR01C2Z4J5lxVYDLhxIb9dPb3fhNSZSxwimZvhHaJ4n3-nVPpkt2PNqoukk View in LinkedIn

SHIFT WORK RISK. “For example, according to the Nurses’ Health Study and case-controlled studies conducted with Norwegian nurses, women that worked night shifts for less than 30 years had a moderately increased risk for breast cancer, and risk was further increased upon working 30 or more years of rotating shift work (relative risk (RR) = 1.36).” https://www.nature.com/articles/s41591-018-0271-8?fbclid=IwAR01C2Z4J5lxVYDLhxIb9dPb3fhNSZSxwimZvhHaJ4n3-nVPpkt2PNqoukk View in LinkedIn

CARCINOGENIC SHIFT WORK. “Circadian disruption has been associated with increased incidence of specific cancers in various epidemiological studies, though the causes and factors linked with this disruption remain somewhat unclear. In 2007, the International Agency for Research on Cancer (IARC) listed “shift work leading to a disruption in circadian rhythm” as a probable human carcinogen, classified as Group 2A.” https://www.nature.com/articles/s41591-018-0271-8?fbclid=IwAR01C2Z4J5lxVYDLhxIb9dPb3fhNSZSxwimZvhHaJ4n3-nVPpkt2PNqoukk View in LinkedIn

DYSCIRCADIA. “Disruptions in biological rhythms result in numerous physiological disorders in organismal homeostasis, with consequences that have been linked to several pathologies, including cancer.” https://www.nature.com/articles/s41591-018-0271-8?fbclid=IwAR01C2Z4J5lxVYDLhxIb9dPb3fhNSZSxwimZvhHaJ4n3-nVPpkt2PNqoukk View in LinkedIn

CLOCK CUES. “The circadian clock sustains self-perpetuating oscillations with a 24-h periodicity and is simultaneously synchronized with external environmental cues such as light, temperature and food intake, the so-called ‘zeitgebers’, or time-givers, that maintain an organism’s proper timekeeping (Fig. 1).” https://lnkd.in/dG2eBWiK View in LinkedIn

CLOCKS AND CANCER. “Epidemiological and clinical data reveal a connection between the disruption of circadian rhythms and cancer that is supported by recent preclinical data.” https://www.nature.com/articles/s41591-018-0271-8?fbclid=IwAR01C2Z4J5lxVYDLhxIb9dPb3fhNSZSxwimZvhHaJ4n3-nVPpkt2PNqoukk View in LinkedIn

MASTER CLOCK. “The circadian clock is a complex cellular mechanism that, through the control of diverse metabolic and gene expression pathways, governs a large array of cyclic physiological processes.” https://www.nature.com/articles/s41591-018-0271-8?fbclid=IwAR01C2Z4J5lxVYDLhxIb9dPb3fhNSZSxwimZvhHaJ4n3-nVPpkt2PNqoukk View in LinkedIn

FRAGMENT FROM NATURE features an interesting report titled ‘The emerging link between cancer, metabolism, and circadian rhythms’ by Selma Masri & Paolo Sassone-Corsi of the University of California at Irvine and INSERM. These findings are potentially very important for the causes as well as the treatment of some cancers. https://www.nature.com/articles/s41591-018-0271-8?fbclid=IwAR01C2Z4J5lxVYDLhxIb9dPb3fhNSZSxwimZvhHaJ4n3-nVPpkt2PNqoukk View in LinkedIn

A TALK, The Force, a whimsical tour of biology. " " https://lnkd.in/eSzQfZBh View in LinkedIn