linkedin post 2017-10-14 04:33:27

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DYSBIOSIS CONCEPT. “ As exemplified by several studies on gut microbial communities, some commensal bacteria of the intestinal flora can become virulent under the influence of diverse factors, such as the actions of other micro-organisms (following horizontal gene transfer between commensal and pathogenic bacteria) or of antibiotics which cause shifts in microbiome composition.” https://lnkd.in/gEfVGaC View in LinkedIn
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linkedin post 2017-10-14 04:28:30

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VAST ECOSYSTEMS. “Recent studies of infectious agents have clearly demonstrated that Koch and Hill's fundamental postulates of “one microbe—one disease” has shown its limits. Indeed, it is now established that many pathogens live and interact with other micro-organisms (not only bacteria, but also protists, fungi, viruses, or phages) in vast communities, all generating and participating in complex interactions that may influence or drive disease processes.” https://lnkd.in/gEfVGaC View in LinkedIn
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linkedin post 2017-10-15 05:30:07

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FROM SOIL TO CLINIC. “The most recent evidence for the transfer of antibiotic resistance genes between the environment and the clinic is provided by Forsberg et al. (2012). Using an innovating metagenomic approach, the authors identified DNA sequences in cultured multi-drug-resistant soil Proteobacteria which had 100% identity to resistance genes found in clinical pathogens, including resistance against β-lactams, tetracyclines, aminoglycosides, sulfonamides, and chloramphenicol.” https://lnkd.in/gEfVGaC View in LinkedIn
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