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HISTORICAL FIRST. "While researching yeast-based functional genomics, Adam became the first machine in history to have discovered new scientific knowledge independently of its human creators." https://lnkd.in/dB_3QTR View in LinkedIn

ROBOTC SYSTEM. "We describe a physically implemented robotic system that applies techniques from artificial intelligence to carry out cycles of scientific experimentation. The system automatically originates hypotheses to explain observations, devises experiments to test these hypotheses, physically runs the experiments using a laboratory robot, interprets the results to falsify hypotheses inconsistent with the data, and then repeats the cycle." https://lnkd.in/d_c-WZa View in LinkedIn

ROBOT ADAM “is capable of: hypothesizing to explain observations; devising experiments to test these hypotheses; physically running the experiments using laboratory robotics; interpreting the results from the experiments; repeating the cycle as required." https://lnkd.in/dB_3QTR View in LinkedIn

ROBOT SCIENTIST ADAM. "The basis of science is the hypothetico-deductive method and the recording of experiments in sufficient detail to enable reproducibility. We report the development of Robot Scientist “Adam,” which advances the automation of both. Adam has autonomously generated functional genomics hypotheses about the yeast Saccharomyces cerevisiae and experimentally tested these hypotheses by using laboratory automation." (Ross King). https://lnkd.in/dJJ9HmD View in LinkedIn

MACHINE SCIENTIST. "Robot scientist makes discoveries without human help. A robot scientist that can generate its own hypotheses and run experiments to test them has made its first real scientific discoveries." https://lnkd.in/dzvEQGa View in LinkedIn

EVE DISCOVERS DRUG. "Ross King from the University of Manchester in England and his team say Eve found a chemical called TNP-470 effectively targets an enzyme that is key to the growth of Plasmodium vivax, one of the parasites that causes malaria. “I didn’t expect to actually find any useful compounds, I thought we’d just demonstrate the AI,” https://lnkd.in/d7vKW9D View in LinkedIn

EVOLVED UPTAKE. "The long-known existence of DNA uptake signal sequences and proteins that bind them, which jointly comprise a discrimination mechanism allowing bacteria to preferentially take up DNA from closely related organisms, is another piece of evidence in support of the view of transformation as an evolved route of gene transfer, apart from the nutritional value of DNA." https://lnkd.in/dSemZpD View in LinkedIn

EVE THE SCIENTIST. "Eve is a prototype system to demonstrate the automation of closed-loop learning in drug-screening and design. Eve's robotic system is capable of moderately high-throughput compound screening (greater than 10,000 compounds per day) and is designed to be flexible enough such that it can be rapidly re-configured to carry out a number of different biological assays." https://lnkd.in/dHmK73K View in LinkedIn

FRAGMENT FROM NATURE continues from last weekend and concludes this weekend on the theme of horizontal gene transfer. Although first described in the 1930s, it was not taken very seriously by biologists until about 1999, when it was increasingly realized that it played an important role in the evolution of many, if not all creatures. And that the main agents of this gene transfer were bacteria, jumping genes, and virus-like agents. Now it is accepted by the mainstream. https://lnkd.in/deYxkt5 View in LinkedIn

HYPOTHESIS TESTING. "Adam conceived 20 hypotheses concerning the identity of genes encoding 13 locally orphan enzymes in S. cerevisiae. Adam tested all these hypotheses on its robotic system and was able to confirm by experimentation, with a high degree of confidence, the correctness of 12 of them." https://lnkd.in/dHmK73K View in LinkedIn