21Sep 2022 by Nigel Fleming No Comments

linkedin post 2021-04-25 05:13:41

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SO ENDS this incredibly short but powerful article that pulls together some of the key ignored questions about the origin of self-sustaining and self-replicating metabolic pathways assembled into autonomous organisms, and proposes a hypothesis for the self-similarity of these pathways across many species. A remarkable article by a remarkable man. https://www.embopress.org/doi/full/10.1002/msb.20145351 View in LinkedIn
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21Sep 2022 by Nigel Fleming No Comments

linkedin post 2021-04-25 05:12:21

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FASCINATING POSSIBILITY. “Thus, it cannot be excluded that a primordial ‘reversed’ glycolysis (that is, a primordial ‘gluconeogenesis’) could have contributed to carbon fixation or facilitated the formation of the complex sugar phosphates required for the assembly of RNA and other biological molecules.” https://www.embopress.org/doi/full/10.1002/msb.20145351 View in LinkedIn
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21Sep 2022 by Nigel Fleming No Comments

linkedin post 2021-04-25 05:10:43

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SUPERFLUOUS LUXURY? “Indeed, there is no need, in principle, of self‐replication, when a given product is continuously re‐made because it is the most stable reaction product—this is the case of all reactions under thermodynamic control.” https://www.embopress.org/doi/full/10.1002/msb.20145351 View in LinkedIn
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21Sep 2022 by Nigel Fleming No Comments

linkedin post 2021-04-27 04:54:31

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THE MISCONCEPTION. “Black holes in equilibrium having the same set of three parameters may still have different ‘internal configurations’...”These quotes betray the same misconception: fundamental physics is about the objective structure of our world, not about our beliefs or our information.” https://lnkd.in/dHGT8xw View in LinkedIn
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21Sep 2022 by Nigel Fleming No Comments

linkedin post 2021-04-25 05:09:08

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WARM WET POND. “It is indeed unlikely that life started in such conditions of extreme dilution of a few molecules in the prebiotic ocean, and some form of compartmentalization might be considered to explain how the necessary local metabolite concentration was achieved.” https://www.embopress.org/doi/full/10.1002/msb.20145351 View in LinkedIn
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21Sep 2022 by Nigel Fleming No Comments
linkedin post 2021-04-26 04:45:54

linkedin post 2021-04-26 04:45:54

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THE END OF KNOWN PHYSICS. “The reader may well worry how the mass-energy of a single black hole could be converted into that for an entire universe, which might well be more than 10(22) times more massive. Indeed, but since some unknown physics is needed in order to circumvent the singularity and alter the fundamental constants, ‘all bets are off’ with regard to the standard conservation laws of conventional physics.” (The Road to Reality, Roger Penrose). https://en.m.wikipedia.org/wiki/The_Road_to_Reality View in LinkedIn
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