linkedin post 2015-06-22 04:38:03

Uncategorized
"SYMMETRY BREAKING in physics describes a phenomenon where (infinitesimally) small fluctuations acting on a system which is crossing a critical point decide the system's fate, by determining which branch of a bifurcation is taken...such transitions usually bring the system from a symmetric but disorderly state into one or more definite states. Symmetry breaking is supposed to play a major role in pattern formation." https://en.m.wikipedia.org/wiki/Symmetry_breaking View in LinkedIn
Read More

linkedin post 2015-06-22 04:32:45

Uncategorized
MEANING OF SYMMETRY. "Einstein's great advance in 1905 was to put symmetry first, to regard symmetry as the primary feature of nature that constrains the allowable dynamic laws. With the development of quantum mechanics in the 1920s symmetry came to play an even more fundamental role." https://lnkd.in/b-9TDnm View in LinkedIn
Read More

linkedin post 2015-06-21 15:35:54

Uncategorized
AGING AND INFLAMMATION. "Prolonged exposure to high levels of circulating TNF compromises the integrity of the BBB. Sensitive techniques now detect the “asymptomatic” presence of bacteria in areas previously thought to be sterile...These “immune-tolerated” bacteria may slowly multiply elsewhere until they elicit a chronic inflammatory response." https://lnkd.in/e-V8G86 View in LinkedIn
Read More

linkedin post 2015-06-21 15:33:12

Uncategorized
ORAL BIOME AND AGING. "Immunosenescence results in increased bacterial load as cell-mediated and humoral immune responses wane. The innate immune system gradually takes over; contributing to the rise in circulating proinflammatory cytokines such as TNF. Maintaining the integrity of the blood-brain barrier (BBB) against a backdrop of increasing bacterial load is important." http://www.researchgate.net/profile/Deborah_Shoemark/publication/264794791_The_Microbiome_and_Disease_Reviewing_the_Links_between_the_Oral_Microbiome_Aging_and_Alzheimer's_Disease/links/53fd9d340cf22f21c2f816ab.pdf View in LinkedIn
Read More

linkedin post 2015-06-21 15:28:00

Uncategorized
ORAL MICROBIOME AND BLOOD-BRAIN BARRIER. "We propose for a subset of AD patients, aging favors the overgrowth of oral anaerobes established earlier in life provoking a pro-inflammatory innate response that weakens the BBB allowing bacteria to spread and quietly influence the pathogenesis of AD." http://www.researchgate.net/profile/Deborah_Shoemark/publication/264794791_The_Microbiome_and_Disease_Reviewing_the_Links_between_the_Oral_Microbiome_Aging_and_Alzheimer's_Disease/links/53fd9d340cf22f21c2f816ab.pdf View in LinkedIn
Read More

linkedin post 2015-06-21 15:20:16

Uncategorized
TASTE RECEPTOR AND METABOLISM. "TAS2R haplotype is associated with altered glucose and insulin homeostasis...a functionally compromised TAS2R receptor negatively impacts glucose homeostasis, providing an important link between alimentary chemosensation and metabolic disease." http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597743/ View in LinkedIn
Read More

linkedin post 2015-06-21 15:17:04

Uncategorized
TASTE RECEPTORS IN THE GUT. "TAS1R and TAS2R-type receptors are expressed in the gustatory system, where they detect sweet- and bitter-tasting stimuli, respectively. These receptors are also expressed in subsets of cells within the mammalian gastrointestinal tract, where they moderate nutrient assimilation and endocrine responses." https://lnkd.in/ewWCUSe View in LinkedIn
Read More

linkedin post 2015-06-21 15:14:00

Uncategorized
TASTE RECEPTORS AND SATIETY. "Taste matters -- bypassing taste receptors boosts insulin and CCK satiety hormone response to food...a relative lack of oral stimulation, due to e.g., caloric beverage or other fast food consumption, can result in overeating by weakening satiety." https://lnkd.in/eET3vB2 View in LinkedIn
Read More