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linkedin post 2021-11-20 05:36:03

RISKY STRATEGY. “In the long term, increased mutation rates are not without evolutionary risk. Opportunities for mutations that greatly improve fitness will eventually run out in the optimization regime. It may then be beneficial to compensate for a hypermutator defect and to become less evolvable in order to lower the genetic load.”

https://www.nature.com/articles/nrg3564

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