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ORIGIN. “However, the initial spontaneous mutation rate is typically low, as discussed above, so that the fitness cost of producing mutations at even a 100-fold higher rate is small. Furthermore, new hypermutator variants frequently arise because loss-of-function mutations in many genes give rise to this phenotype.” https://www.nature.com/articles/nrg3564 View in LinkedIn

FRAGMENT FROM NATURE continues from last weekend and ends this weekend on the theme of the very heart of evolution, inheritance with variation, or random gene mutation. The other face of evolution, natural selection, is performed by differential death and survival. Generate diversity, select and repeat. Generate diversity, select and repeat. This is evolution at its core. View in LinkedIn

Magnificent grove of plane trees in the Girona Devesa park. View in LinkedIn

MY EPITAPH. “Nothing perishes in this world; but things merely vary and change their form. To be born, means simply that a thing begins to be something different from what it was before; and dying, is ceasing to be the same thing. Yet although nothing retains long the same image, the sum of the whole remains constant.” (Ovid, Metamorphoses Book XV, 8 AD). https://lnkd.in/dhjhdUAs View in LinkedIn

NET EFFECTS. “Annihilation would produce no net contribution. Similarly matter created very close to the origin, (without leakage, case iii) on the (-) side would approach the (+) side by simple motion in time forward.” https://lnkd.in/gDaxUYAS View in LinkedIn

LEAKING BETWEEN MIRROR WORLDS. “The following cases designated by roman numerals make no direct contribution to either preponderance. In case (i) antimatter leaking by quantum uncertainty from (-) time to (+) time would then move backwards in time toward the origin, approaching equal quantities of matter in case (ii) moving forward in time toward the origin on the (-) side of the origin after leaking by quantum uncertainty from (+) time.” https://lnkd.in/gDaxUYAS View in LinkedIn

MIRROR EXPLANATION. “In case (B) antimatter leaking from (+) to (-) time moves backward in time away from the origin and after many annihilations makes a contribution to the antimatter preponderance on the (-) side.” https://lnkd.in/gDaxUYAS View in LinkedIn

MIRROR EXPLANTATION. “At times very near the origin the following mechanism is suggested. In case (A) matter leaking via quantum uncertainty from the (-) side of the origin to the (+) side moves forward in time away from the origin and after many annihilations makes a contribution to the preponderance of matter on the (+) side.” https://lnkd.in/gDaxUYAS View in LinkedIn

MIRROR WORLDS. “The probability of a particle or antiparticle created on one side of the origin being found on the other would rapidly decrease as space-time expands, since the required time displacement from the origin would increase while the extent of quantum uncertainty in time would not.” https://lnkd.in/gDaxUYAS View in LinkedIn

GIRONA CATHEDRAL. “The cathedral's interior includes the widest Gothic nave in the world, with a width of 23 metres (75 ft), and the second-widest of any church after that of St. Peter's Basilica (for comparison, the width of the nave of Reims Cathedral is 14.65 m, Saint-Étienne de Sens, 15.25 m and 12 m, in Notre Dame de Paris).” https://lnkd.in/gvmpNwbx View in LinkedIn