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DNA PROGRAMMING OF MITOCHONDRIA "generally regulates all of the proteins associated with a metabolic or biosynthetic pathway associated with a given function." In other words, the mitochondrion is the master switch of the cell. The same is true of the chloroplast in plants. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209511/ View in LinkedIn

BACTERIA have been reprogramming living hosts for millions of years. We are simply catch up with these Masters of the Universe. View in LinkedIn

MASTER-SWITCH FLEXIBILITY. "The nuclear DNA transcriptional programming of the mitochondrion proteome varies dramatically between tissues depending on its functional requirements," and varies considerably in disease. This adaptation by ancient bacteria to a highly complex host is very intimate and complete. https://lnkd.in/eE2z3WE View in LinkedIn

DIGITAL NERVOUS SYSTEM. “As the age of the digital nervous system dawns, Grok represents the type of technology that will convert massive data flows into value.” (From Numenta, by PalmPilot co-founder Jeff Hawkins). Watch this space. https://lnkd.in/erRbqPk View in LinkedIn

BUT A PASSENGER. Chloroplasts and mitochondria, the indispensable powerhouses of every cell, and perhaps even the very nucleus, let alone our microbiome within, are likely all of microbial origin. As much as originating from apes hurt Victorian religious sensibilities, this new worldview would have shattered them. http://www.poets.org/poetsorg/poem/force-through-green-fuse-drives-flower View in LinkedIn

MIGHTY CONFLUENCE. "The physical and computational world will merge." https://lnkd.in/dHbJvdK View in LinkedIn

MORE THAN THE MICROBIOME, the knowledge that bacteria are intimately and continuously guiding the ship of life is profound. Humanity's hubris has barely recovered from Darwin, let alone these microbial hijackings. "The force that through the green fuse drives the flower Drives my green age; that blasts the roots of trees Is my destroyer." (Dylan Thomas). http://www.poets.org/poetsorg/poem/force-through-green-fuse-drives-flower View in LinkedIn

VIRAL ORIGIN OF OUR NUCLEUS. It is thought, although hotly debated, that the nucleus of eukaryotic nucleus, the very supercomputer of all cells, arose from a DNA virus. What remains of our cells that are not powered and masterminded by microorganisms is vanishingly small. http://en.m.wikipedia.org/wiki/Viral_eukaryogenesis View in LinkedIn

ORIGIN OF MITOCHONDRIA AND CHLOROPLASTS. There is substantial evidence to support the idea that ancient bacteria entered animal and plant cells, and in doing so, became the most important organelle in the cell. Today, they retain enough of their autonomous identity to be seen as clearly distinct, but are intimate symbiotic creatures living with us. https://lnkd.in/eZ33NPk View in LinkedIn

THE REPROGRAMMING OF HOSTS by ancient bacteria is one of the most astonishing facts of biology. These deceptively simple creatures figured out, not once, but twice (mitochondria and chloroplasts), separately, how to completely reprogram host cells. Granted, the process has taken millions of years, but the incredible success of both events makes these bacterial reminants the masters of plants and animals, and thereby, the planet earth. View in LinkedIn